Purpose: To evaluate risk factors (hypertension, diabetes mellitus, and current tamsulosin, alfuzosin, terazosin, or doxazosin use) for intraoperative floppy iris syndrome (IFIS) in patients undergoing phacoemulsification cataract surgery.
Design: Systematic review and meta-analysis of the literature.
Participants: Seventeen eligible studies (17 588 eyes) examining the association between IFIS and risk factors.
Conclusions: This meta-analysis has highlighted a hierarchy concerning the role of α1-blockers in IFIS, indicating an extremely sizeable effect size of tamsulosin; this may entail important physiologic implications. Alfuzosin, terazosin, and doxazosin presented with comparable effect sizes. Hypertension, but not diabetes mellitus, emerged as a risk factor for IFIS.
Design: Systematic review and meta-analysis of the literature.
Participants: Seventeen eligible studies (17 588 eyes) examining the association between IFIS and risk factors.
Conclusions: This meta-analysis has highlighted a hierarchy concerning the role of α1-blockers in IFIS, indicating an extremely sizeable effect size of tamsulosin; this may entail important physiologic implications. Alfuzosin, terazosin, and doxazosin presented with comparable effect sizes. Hypertension, but not diabetes mellitus, emerged as a risk factor for IFIS.
Posts
Post a Comment