The iStent trabecular micro-bypass stent is an investigational device in clinical trials in the United States for the treatment of glaucoma in patients undergoing cataract surgery. It is delivered ab interno through a clear corneal incision, advanced through the trabecular meshwork and implanted into Schlemm canal where it creates a pathway for aqueous humor to drain directly from the anterior chamber into Schlemm canal. The procedure avoids any manipulation of the iris, conjunctiva, or sclera, and thus preserves all other surgical and medical options. Stent implantation requires the device, its applicator, and a manual gonioprism. Other recently developed techniques for surgery on the angle require high-technology instrumentation.
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